OF ALLIUM SATIVUM AS ANTIBIOTIC AND CHLORAMPHENICOL ANTIBIOTIC ON
HEMATOLOGICAL AND BIOCHEMICAL CHANGES IN OREOCHROMIS NILOTICUS
Elsayed A.M. Shokr and Fathy, A.
Fish Physiology Department, Central Laboratory for Aquaculture Research, Agriculture Research Center, Giza, Egypt.
Received 11/ 11/ 2018
Accepted 18/ 12/ 2018
The present investigations show the effects of garlic and chloramphenicol on physiological changes in Oreochromis niloticus. Fish (100gm±1) were classified into seven groups control group and six treated groups, with three replicates each. Treatment groups had a different level of garlic (Allium sativum) (4, 8, and 16gm/kg diet) and chloramphenicol (10, 20, and 40mg/kg diet) added to their diets; the control group diet was free from garlic and chloramphenicol. Blood parameters, erythrocyte count (RBC), hematocrit and hemoglobin content in fish treated with 16gm/kg garlic and 20mg/kg chloramphenicol were significantly higher than in control. There were no significant differences in the mean corpuscular volume (MCV) and mean corpuscular hemoglobin concentration (MCHC). However, the values obtained for the white blood cells (WBCs) were significantly higher for all groups treated with garlic and chloramphenicol than that control group. There was significant increase in the total protein but decreased in total lipids, cholesterol and triglycerides levels in the groups treated with 16gm/kg garlic and 20mg/kg chloramphenicol than that control group. Plasma glucose, AST, ALT, ALP, uric acid and creatinine were decreased significantly with increasing doses of garlic and chloramphenicol than that control group. The values obtained for the calcium (Ca), sodium (Na) and potassium (K) were significantly higher for all groups treated with garlic and chloramphenicol than that control group. garlic and chloramphenicol administration led to significant hypolipidaemia, accompanied by decreases in liver total lipids and a significant rise in the white muscle total lipids. Garlic and chloramphenicol administration led to the liver and muscle TFAA decreased. Thus, it can be concluded that the treatment of fish with garlic and chloramphenicol can improve fish health by increase the activity of fish due to improvement the changes in blood aspects. Also, the garlic is natural, cheaper and better than chloramphenicol for improvement health of fish.
Keyword: Oreochromis niloticus, garlic, chloramphenicol, blood aspects.